Wednesday, July 11, 2018

Diabetes and Risk of Cancer

Patients with diabetes mellitus are at increased risk of cardiovascular complications such as heart attack, stroke, peripheral arterial disease etc. Commonly, the cause of death in diabetes is due to cardiovascular events.

Does diabetes increases risk of cancer in addition of increased risk of cardiovascular diseases? This important question was explored in this interesting study of over half-million Chinese. Investigators enrolled patients with and without diabetes and without any prior diagnosis in the study between 2004-2008 and then followed them until the end of 2013 for development of any cancer. During the follow-up period, they found more than 17,000 cases of cancer. Diabetes was associated with an increased risk of all-cause cancer and site-specific cancer.

Diabetes increased the risk of overall cancer by 13%, of liver cancer by 51%, of the pancreatic cancer by 76% and of the breast cancer by 21%. Investigators further reported that higher random blood glucose levels were associated with increased risk of cancer. Perhaps, it is the elevated blood glucose levels in diabetics that is responsible for cancer.

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